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Slowed Intestine Motion. Paralytic ileus is actually a variety of ileus wherever your intestines are not able to shift meals by them. Promethazine/codeine will make this condition even worse.

Dispose of expired, undesired, or unused promethazine/codeine without delay by taking your drugs to a certified DEA-registered collector or drug choose again method.

The mix of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric clients less than six yrs of age. Concomitant administration of promethazine solutions with other respiratory depressants has an Affiliation with respiratory depression, and in some cases death, in pediatric sufferers.

Codeine: In individuals acquiring MAO inhibitors, an initial compact test dose is sensible to permit observation of any too much narcotic consequences or MAOI interaction.

It's soluble in water and check here freely soluble in Alcoholic beverages. It's a molecular fat of 320.88, a molecular method of C17H20N2S•HCl, get more info and the following structural formula:

Discontinuation of a concomitantly made use of cytochrome P450 2D6 inhibitor might result in a lower in codeine plasma concentration and a rise in active metabolite morphine plasma focus which could enhance or prolong adverse reactions and should trigger potentially deadly respiratory depression.

Promethazine/codeine get more info could also be utilized for other disorders as determined by your healthcare supplier.

The mixture of promethazine hydrochloride and codeine phosphate is contraindicated click here in pediatric individuals under 6 a long time of age, due to the fact The mix may bring about fatal respiratory melancholy During this age inhabitants (see WARNINGS Box Warning and Use in Pediatric Clients).

When useful for an prolonged time, this medication may well not do the job in addition and could involve different dosing. Communicate with your medical professional if this medication stops Functioning well.

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Promethazine administered to a Expecting female within two weeks of delivery may possibly inhibit platelet click here aggregation within the newborn.

The decision to make it prescription-only was designed following an MHRA consultation with industry experts and healthcare experts, and comes amid reviews of misuse of the opioid.

An anticholinergic medication, which includes antihistamines and medicines generally used for overactive bladder, Parkinson’s disease, or stomach problems